HELP with Opiate Tolerance

This video segment, presented by Dr. William G. Brose, MD, describes critical issues of opiate tolerance for chronic pain sufferers.

Trackback URL

, ,

18 Comments on "HELP with Opiate Tolerance"

  1. superotter77
    05/03/2014 at 5:42 pm Permalink

    Unbelievable. Opiophobia, which this doctor is clearly expressing, is a
    crime against humanity. Drug “holidays” are torture and completely
    unnecessar, as are ceiling doses of pain meds, since everyone has different
    tolerances and pain levels. To all you able-bodied opioid fear-mongers, try
    having your testicles in a vice grip that’s constantly being tightened, and
    then not allowed pain relief for it. Chronic pain sufferers need WHATEVER
    DOSES IT TAKES to manage their pain, period!!

  2. superotter77
    05/03/2014 at 6:40 pm Permalink

    Unbelievable. Opiophobia, which this doctor is clearly expressing, is a
    crime against humanity. Drug “holidays” are torture and completely
    unnecessar, as are ceiling doses of pain meds, since everyone has different
    tolerances and pain levels. To all you able-bodied opioid fear-mongers, try
    having your testicles in a vice grip that’s constantly being tightened, and
    then not allowed pain relief for it. Chronic pain sufferers need WHATEVER
    DOSES IT TAKES to manage their pain, period!!

  3. surgeyX
    05/03/2014 at 7:33 pm Permalink

    IF every opiate receptor in your body is full, whether it’s an agonist or
    antagonist, where are they going to go? Answer that.

  4. Seeking The Truth
    05/03/2014 at 8:26 pm Permalink

    whithdrawl is not a good thing to do to someone its dr’s that gave me these
    drugs never warning of addiction or tolerance the last thing you want to do
    to someone is cause them whithdrawls when they are already suffering as it
    is that is just adding more stress and suffering to the patient I wish dr’s
    would understand this is not a thing we wanted and most of us didn’t know
    so why put ppl through withdrawl that is cruel to me

  5. drewfuss2121
    05/03/2014 at 8:58 pm Permalink

    as an MS patient who has been hospitalized with viral meningitis, numerous
    spinal-taps, and with several staph-infections requiring cellulitis
    surgery, I’ve noticed that before surgeries the dr’s like to give fentanyl.
    Had zero effect on my pain. Don’t know why. But I DO know that fetanyl is
    nothing to mess with. It’ll kill ya! Just hope other patients like myself
    have a better quality of life. Thats all I’m sayin…

  6. jimsutube123
    05/03/2014 at 9:31 pm Permalink

    no full opiate aganost has any cieling with increased dose is increased
    side effect, notably contipation and sedation, unlike buprenorphine and
    other partial opiate agonist which do have a ceiling effect. please do me a
    favor a research it so and when you see your wrong you wont have to bother
    responding and looking stupid.

  7. CNSagent
    05/03/2014 at 10:26 pm Permalink

    He’s a perfect way to limit the dose needed for effective opioid analgesic
    releif: prescribe synthetic cannabinoids (or natural is state does not
    prohibit) along with opioids. Cannabinoids produce cross-tolerancce between
    opioids, but ironically, only a small dose of an opioid is needed when
    taken in combination with cannabis or a cannabinoid. Combining cannabinoids
    with opioids would not only lower the amount of opioids needed, but it
    would offer patients a better chance at pain releif.

  8. hartbeat00000
    05/03/2014 at 11:02 pm Permalink

    Hi. In Canada alone we pop 466,000 prescription painkillers daily more than
    any other country per capita other than USA and Belgium. Its the drugs the
    street kids use now more than any other drugs. And seniors, who have a lot
    of pain get hooked. hartbeatthehippie

  9. JonesGOP1
    05/03/2014 at 11:06 pm Permalink

    I would LOVE toknow the doc who was giving her 1000mg per day, he’s my
    hero. when I used to go to a methadone clinic I got up to 230mg daily and
    before Thanksgiving ’05 I got a week take home doses and took 4 of them
    right off the bat That was 920mg at once and I was HAMMERED for about 2
    days as I had taken a handful of xanax with this, so it is definately
    possible to take that much Methadone and live, the xanax just makes it more
    fun, but of course I don’t recommend it to pansies 😉

  10. JonesGOP1
    05/03/2014 at 11:33 pm Permalink

    Whoever told you it stops being effective around 300 is a LIAR there is NO
    ceiling effect on Methadone

  11. surgeyX
    06/03/2014 at 12:24 am Permalink

    @mynthon11 I think you either need to learn English or make use of a spell
    checker.

  12. jimsutube123
    06/03/2014 at 1:11 am Permalink

    over time our brains when indroduced to increasing amount of opiates create
    new receptors for the opiods to attach. which is one of the reasons people
    experience PAWS or post acute withrawl syndrome after an opiate detox. at
    least thats what the medical journals i have to read say

  13. KilonBerlin
    06/03/2014 at 1:41 am Permalink

    @surgeyX why not? I get 140mg officialy and I took one day 500mg without
    any dangerous effects (don’t do this @ home kids…), its extreme of course
    but I think thats why he is talking about it, the hardest case he can
    remember..

  14. JonesGOP1
    06/03/2014 at 1:51 am Permalink

    OH sorry Jimspolesmoke I know I forgot to give credit where it is due and
    your Mom really helped me enjoy my high ass I pounded her poop shute all
    evening then Robot Andrew Sullivan came along and gave her the AIDS. LOL
    tell the bitch I said HIGH! hahaha

  15. Seeking The Truth
    06/03/2014 at 2:42 am Permalink

    Hi I was switched from ten mg oxycontin extended release to Fentanyl 50mcg
    patches was I put on this patch due to Opoid tolerance and what is Fentanyl
    is it an opoid or a synthetic opoid I dont understand why I was put on the
    patches

  16. chrissys31
    06/03/2014 at 3:24 am Permalink

    I find this to be a very educational video for myself being a methadone
    patient for addiction to opiate pills and I am going through this problem
    now but not as extreme but i am on 114mgs and have been on methadone for 4
    yrs almost and this is the highest I have been and I really feel I need
    more but thats what I am doing is creating a ceiling because I know the
    higher I go I will just get a tolerence to it after awhile. God I hate
    opiates lol!

  17. laetrille
    06/03/2014 at 4:01 am Permalink

    you suck

  18. surgeyX
    06/03/2014 at 4:33 am Permalink

    That’s incorrect — you only have so many opiate receptors throughout your
    body, if they are ALL occupied then any more drug taken has nowhere to go.
    This differs from drug to drug and from person to person, but yes,
    methadone DOES have a cieling.

Hi Stranger, leave a comment:

ALLOWED XHTML TAGS:

<a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>

Subscribe to Comments